Showing 20 results for Researcher: Hugh M. O'Neill
May 13, 2025
1 MIN READ
SANS identified new bf-ETF conformations that facilitate rapid interconversion between functional states, enabling efficient electron bifurcation.
March 25, 2025
6 MIN READ
Scientists at ORNL and the University of Cincinnati achieved a breakthrough in understanding the vulnerability of microbes to the butanol they produce during fermentation of plant biomass. The discovery could pave the way for more efficient production of domestic fuels, chemicals and materials.
February 13, 2025
6 MIN READ
Hugh O’Neill’s lifelong fascination with the complexities of the natural world drives his research at ORNL, where he’s using powerful neutron beams to dive deep into the microscopic realm of biological materials and unlock secrets for better production of domestic biofuels and bioproducts.
March 27, 2024
1 MIN READ
Evidence for lignin–carbohydrate complexes (LCCs) formed between lignin and pectin was obtained by synthesis and biophysical characterization of deuterated lignin–pectin composites.
December 27, 2023
7 MIN READ
The 2023 top science achievements from HFIR and SNS feature a broad range of materials research published in high impact journals such as Nature and Advanced Materials.
June 15, 2023
1 MIN READ
This is the first work to unveil the self-assembly of proteins through adsorbate-adsorbate interactions across pore apertures of a metal-organic framework (MOF) via small-angle neutron scattering (SANS).
March 28, 2023
4 MIN READ
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.
June 10, 2021
4 MIN READ
Scientists at Oak Ridge National Laboratory have uncovered how the SARS-CoV-2 virus evades the human immune system by studying the interaction between a viral protein (PLpro) and a key immune protein (ISG15). These insights could guide the development of therapeutic drugs to block this interaction, enhancing the body’s ability to combat the virus.
November 16, 2020
5 MIN READ
Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.
October 27, 2020
4 MIN READ
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.
July 7, 2020
5 MIN READ
Scientists at ORNL used neutron scattering and supercomputing to better understand how an organic solvent and water work together to break down plant biomass, creating a pathway to significantly improve the production of renewable
June 25, 2020
5 MIN READ
A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.