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Showing 12 results for Researcher: Richard J. Giannone

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August 6, 2026

6 MIN READ

New platform speeds bacterial gene mapping for better biotech design

Oak Ridge National Laboratory researchers developed a high-throughput microbial QTL mapping platform that combines synthetic biology, AI, automation and gene editing to identify the genetic basis of complex bacterial traits up to 10 times faster than previous methods. The platform enables more precise engineering of microbes for applications including specialty chemicals manufacturing, bioenergy and critical minerals recovery, and is available for licensing.
January 17, 2024

7 MIN READ

Fungal ‘bouncers’ patrol plant-microbe relationship

New computational framework speeds discovery of fungal metabolites, key to plant health and used in drug therapies and for other uses.
March 15, 2023

4 MIN READ

Research team proves bacteria-killing viruses deploy genetic code-switching to deceive hosts

Scientists at ORNL have confirmed that bacteria-killing viruses called bacteriophages deploy a sneaky tactic when targeting their hosts: They use a standard genetic code when invading bacteria, then switch to an alternate code at later stages of
March 28, 2022

12 MIN READ

CBI early career program develops next generation of bioenergy leaders

The Center for Bioenergy Innovation at ORNL offers a unique opportunity for early career scientists to conduct groundbreaking research while learning what it takes to manage a large collaborative science center.
February 21, 2022

6 MIN READ

Carbon-negative platform turns waste gases into valuable chemicals

A team of scientists from LanzaTech, Northwestern University and ORNL have developed carbon capture technology that harnesses emissions from industrial processes to produce acetone and isopropanol
July 9, 2021

6 MIN READ

Population-specific diversity within fungi species could enable improved drug discovery

Scientists at ORNL and the University of Wisconsin–Madison have discovered that genetically distinct populations within the same species of fungi can produce unique mixes of secondary metabolites, which are organic compounds with applications in
June 29, 2021

5 MIN READ

New enzyme breaks down waste for less expensive biofuels, bioproducts

In a step toward increasing the cost-effectiveness of renewable biofuels and bioproducts, scientists at ORNL discovered a microbial enzyme that degrades tough-to-break bonds in lignin, a waste product of biorefineries.
April 8, 2021

6 MIN READ

Rich Giannone: Solving puzzles through proteins

Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.
April 2, 2018

2 MIN READ

Biology—Lurking mouth microbes

An Oak Ridge National Laboratory-led team cultivated a novel oral microbe, Desulfobulbus oralis, present in adults with periodontitis, an advanced gum disease that affects nearly half of all adults worldwide.
April 2, 2018

2 MIN READ

Biology—Lurking mouth microbes

An Oak Ridge National Laboratory-led team cultivated a novel oral microbe, Desulfobulbus oralis, present in adults with periodontitis,an advanced gum disease that affects nearly half of all adults worldwide. By integrating genomic and metabolic techniques with classical microbiology, ...
March 1, 2017

3 MIN READ

Understanding how different plant-derived sugars affect the physiology of a biofuel-producing microbe

Researcher’s at the Department of Energy’s Oak Ridge National Laboratory in the BioEnergy Science Center (BESC) are working to understand how different sugars derived from plant material affect the metabolism of a cellulolytic, biofuel-producing
February 27, 2017

2 MIN READ

Microbial attachment to cellulose substrate produces widespread gene expression changes

Researchers in the BioEnergy Science Center (BESC) are studying the microbial attachment to cellulose substrate which produces widespread gene expression changes. Unlike the majority of biofilm forming bacteria, C. thermocellum adheres to substrata that also provide its major carbon and en...

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New platform speeds bacterial gene mapping for better biotech design

Fungal ‘bouncers’ patrol plant-microbe relationship

Research team proves bacteria-killing viruses deploy genetic code-switching to deceive hosts

CBI early career program develops next generation of bioenergy leaders

Carbon-negative platform turns waste gases into valuable chemicals

Population-specific diversity within fungi species could enable improved drug discovery

New enzyme breaks down waste for less expensive biofuels, bioproducts

Rich Giannone: Solving puzzles through proteins

Biology—Lurking mouth microbes

Biology—Lurking mouth microbes

Understanding how different plant-derived sugars affect the physiology of a biofuel-producing microbe

Microbial attachment to cellulose substrate produces widespread gene expression changes