August 2025

Journal

RefAHL: a curated quorum sensing reference linking diverse LuxI-type signal synthases with their acyl-homoserine lactone products

By:
Schaefer, Amy; Murdock, Ethan; Pelletier, Dale A; Harwood, Caroline; Greenberg, E.; Puri, Aaron
Journal Name:
Microbiology Resource Announcements
Page Number:
1-4
Volume:
14
Issue Number:
6
Publication Date:
August 8, 2025
View DOI Listing:
https://doi.org/10.1128/mra.00407-25

Abstract

Some bacteria use acyl-homoserine lactone (AHL) signals in quorum sensing, a type of cell-cell communication. Here, we present “RefAHL,” an updated, curated collection of LuxI-type AHL synthases with their AHL products and associated metadata. RefAHL is publicly available as a community resource to help catalog LuxI-type diversity encoded in (meta) genomic data.


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